Every named stream in the Adirondack Park — the feeder waters that line the High Peaks valleys and fill the ponds.
East Branch Cold Brook drains west through the working forest between Saranac Lake and Tupper Lake — a mid-sized tributary feeding the Cold Brook drainage system that eventually meets the Raquette River. It's the kind of unnamed-on-most-maps stream that defines the interior Adirondacks: functional, not scenic; valuable more for what it feeds than for any reason to visit. No fish data on record, no formal access, no reason to name it except that every branch of every brook is cataloged somewhere, and this is one of them. If you're bushwhacking the Cold Brook corridor or cutting timber lease roads on a map, you'll cross it.
The East Branch of the Little Salmon River drains north through the backcountry between Saranac Lake and Paul Smiths — a small feeder system that sees more moose than anglers. No established trail follows the stream itself, and access typically means bushwhacking off seasonal logging roads or working upstream from the main stem. The watershed is forested corridor country, the kind of water that shows up on a DEC map but not in a trip report. If you're targeting wild brookies in the upper tributaries of the Little Salmon drainage, this is one of several branches worth exploring with a topo and low expectations for size.