Every named river in the Adirondack Park — the Hudson, the Moose, the Raquette, the Sacandaga, and the rivers that drain the High Peaks.
The East Branch of the Saint Regis River drains a patchwork of ponds and wetlands north of Saranac Lake, threading through a mix of state forest land and private holdings before joining the main stem near Paul Smiths. It's a working river — quiet water, alder tangles, beaver activity — more paddled by locals than advertised in guidebooks. Access points are scattered and often require permission or local knowledge; the DEC stocks brook trout in some tributaries, but fish data for the East Branch itself is thin. If you're exploring the Saint Regis Canoe Area, you're more likely intersecting this river by portage than by design.